Scientist

Payrate: $35.00 - $37.00/hr.

Summary:
This Contract Scientist will report to a Principal Scientist in the Discovery Genomics team of Target Discovery & Biology (TD&B). This role will support higher throughput, improved data management, and faster turnaround for projects analyzed within the TD&B group.

Responsibilities:

• Support routine computational analysis of functional genomics and transcriptomics datasets using established internal pipelines and reporting systems.
• Assist with experimental registration, source sample tracking, and data management for NGS-based workflows to ensure data retention, visibility, and accessibility.
• Manage workflow and data entry in Benchling OEMS for pooled gene perturbation, amplicon-seq, bulk RNA-seq, and related NGS experiments.
• Process pooled genomic perturbation screen data, including raw FASTQ files, using established NextFlow pipelines and internal gene-edited reporting systems.
• Support future arrayed perturbation screening efforts by running established analytical pipelines once developed and implemented.
• Process Perturb-seq datasets by converting raw FASTQ files into count tables using established Cell Ranger workflows.
• Support bulk RNA-seq routine by downloading data from CROs, processing samples through the internal bulk RNA-seq pipeline and generating reports using established RNA-seq reporting workflows.
• Assist with transcriptomic assessment of edited clones using existing analysis pipelines.
• Partner closely with the manager and TD&B team members to prioritize analyses, troubleshoot routine issues, and ensure timely project completion.
• Maintain organized records of analyses, inputs, outputs, and reports to support reproducibility, data integrity, and downstream interpretation.

Preferred Qualifications:

• Degree or experience in bioinformatics, computational biology, genomics, genetics, biology, data science, or related discipline.
• Familiarity with NGS data types, including pooled gene perturbation screens, bulk RNA-seq, amplicon-seq, Perturb-seq, or other functional genomics workflows.
• Experience running established computational pipelines and working with structured data outputs.
• Familiarity with sequencing file formats and analysis outputs, including FASTQ files, count matrices, and standard NGS reports.
• Experience with Benchling, sample tracking systems, or other experimental registration/data management platforms.
• Experience working in Unix/Linux environments and cloud-based computing platforms, including AWS, is preferred.
• Basic programming or scripting experience in R, Python, or shell scripting is preferred.
• Strong attention to detail and commitment to data integrity, reproducibility, and documentation.
• Ability to work independently on routine analyses while communicating regularly with the manager and project teams.
• Strong written and verbal communication skills, with the ability to collaborate effectively in a cross-functional research environment.

Top 3 Must Have Skill Sets:

• Ability to run established computational workflows and pipelines
• Diligence and organization for metadata entry
• Ability to execute on a list of tasks without close supervision

Pay Transparency: The typical base pay for this role across the U.S. is: $35.00 - $37.00 /hr. Non-exempt positions are eligible for overtime at a rate of 1.5 times the base hourly rate for all hours worked in excess of 40 in a work week, or as required by state or local law. Final offer amounts, within the base pay set forth above, are determined by factors including your relevant skills, education and experience. Full-time employees are eligible to select from different benefits packages. Packages may include medical, dental, and vision benefits, health savings accounts with qualified medical plan enrollment, 10 paid days off, 3 days paid bereavement leave, 401(k) plan participation with employer match, life and disability insurance, commuter benefits, dependent care flexible spending account, accident insurance, critical illness insurance, hospital indemnity insurance, accommodations and reimbursement for work travel, and discretionary performance or recognition bonus. Sick leave and mobile phone reimbursement provided based on state or local law.

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